منابع مشابه
Leukocyte- and endothelial-derived microparticles: a circulating source for fibrinolysis.
BACKGROUND We recently assigned a new fibrinolytic function to cell-derived microparticles in vitro. In this study we explored the relevance of this novel property of microparticles to the in vivo situation. DESIGN AND METHODS Circulating microparticles were isolated from the plasma of patients with thrombotic thrombocytopenic purpura or cardiovascular disease and from healthy subjects. Micro...
متن کاملClotting and fibrinolysis.
Vascular disease accounts for more than 50% of deaths and in most cases the cause lies in obstruction to blood flow by the twin perils of atheroma formation and thrombosis. The major constituents of thrombi are platelets and fibrin, together with trapped red cells and other elements. Our main antithrombotic drugs are the antiplatelet agents to prevent platelets sticking together; anticoagulants...
متن کاملSmoking and fibrinolysis.
In order to study the fibrinolytic activity of vein walls in smokers and nonsmokers, 71 randomly selected heavy smokers, i.e., smoking more than 15 g tobacco per day, and 41 nonsmokers from the population group "Men born in 1914 residing in Malmo" were invited to undergo a health examination. When examined after 12 hours' abstention from tobacco, the smokers were found to have the same fibrinol...
متن کاملFibrinolysis and gastrointestinal haemorrhage.
Most human tissues contain fibrinolytic activators. The alimentary tract organs, however, were not considered to be a site of importance and were not included in a comprehensive survey of human necropsy tissues studied by Albrechtsen.1 But since Cox, Poller, and Thomson2 found local organ fibrinolysis in the stomach and free plasmin in gastric vein blood there has been much interest in the poss...
متن کاملThrombin and fibrinolysis.
When the activities of the coagulation and fibrinolytic cascades are properly regulated, so that fibrin (FN) deposition and removal are properly balanced, the vascular system is protected from catastrophic blood loss at the site of an injury, while its fluidity is ensured elsewhere. When these activities are not properly regulated, however, the organism is subjected to either excessive bleeding...
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ژورنال
عنوان ژورنال: Seminars in Thrombosis and Hemostasis
سال: 2016
ISSN: 0094-6176,1098-9064
DOI: 10.1055/s-0036-1592301